Molecular Imaging and Structural Biophysics

Our research group integrates high-resolution optical engineering, custom computational structural modeling, and biophysical methods to visualize dynamic biological mechanisms at sub-nanometer scales.

We engineer novel interferometric and single-molecule fluorescence optical setups to capture conformational changes in biomolecular complexes with spatial precision.

Custom computational tools process raw quantitative experimental datasets into dynamic structural models, resolving atomic details in flexible protein assemblies.

Translating physical principles into functional fluorescent biosensors and molecular probes to monitor real-time cellular signaling pathways.

Every experimental pipeline combines custom hardware instrumentation with open-source software packages developed in-house. By coupling direct physical measurements with automated data processing workflows, our protocols deliver reproducible quantitative insights into complex biomolecular machinery.

We emphasize rigorous scientific validation through multi-modal biophysical characterization. Computational algorithms undergo systematic benchmarking against established structural databases to ensure robust predictions across diverse macromolecular systems.

Review our complete repository of journal articles, computational code repositories, and structural datasets.